The HELM Antibody Editor allows the user to visualise and manipulate antibody structures.
It includes many features, but the ability to detect domains and add structural features such as Cys-Cys bonds is central.
HAbE2 was released to GitHub in January 2018. Many thanks again to Roche who have continued to develop the antibody editor and have donated their efforts to the open source community.
Key new features include:
The following documents provide an overview of the antibody editor and the functionality available.
HELM Antibody Editor: What is it, what can it do? (slides)
Extended Overview of HAbE (slides)
User guide for the HELM Antibody Editor (document)
All code is published in GitHub
HAbE2 : https://github.com/PistoiaHELM/HELMAntibodyEditor2
Example Plugins : https://github.com/PistoiaHELM/HELMAntibodyEditor2Plugin
Compiled code - try it for yourself
How to connect to the domain / mutation / rule libraries when located in a database
Custom Master Libraries in HAbE v2.pdf
How to write plugins e.g. to store the antibody constructs in databases instead of XML files
How to write plugins for HAbE v2.pdf
Licenses and restrictions
HELM is an open source project released under the MIT license. However HAbE2 currently has one dependency on third party tools.
- HAbE2 requires yFiles for Java version 2.6 or higher and GraphML extension from yWorks. If you wish to use the compiled software directly there is no need to buy a licence. If you wish to develop the software for your own use, trial versions of such libraries can be downloaded from yWorks at www.yworks.com. You need to update the ant build file with regard to yfiles.dir and jar file names before compiling and running the project.