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The HELM Antibody Editor allows the user to visualise and manipulate antibody structures.

 It It includes many features, but the ability to detect domains and add structural features such as Cys-Cys bonds is central.


 **New** HAbE2

HAbE2 was released to GitHub in January 2018. Many thanks again to Roche who have continued to develop the antibody editor and have donated their efforts to the open source community.

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Key new features include:  

Info

MonomerDesigner: 
Design your own new monomer for the HAbE and save it into your local monomer store

ADCDesigner
Attach chemical molecules to a peptide at the N- or C-terminal end, on specific amino acids or on an amino acid type with a statistical binding ratio
 

Domain Protease Reaction
Cut your antibody according to the protease sequence motif

Sortase Coupling
Split your antibody according to a peptide motif and connect it with a ligand

Biotinylation
Covalently attach biotin to AVI-tag

Domain Protease Reaction
Cut your antibody according to the protease sequence motif

Sortase Coupling
Split your antibody according to a peptide motif and connect it with a ligand

Biotinylation
Covalently attach biotin to AVI-tag


Getting started

All about HAbE

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Technical information

How to connect to the domain / mutation / rule libraries when located in a database

Custom Master Libraries in HAbE v2.pdf

How to write plugins e.g. to store the antibody constructs in databases instead of XML files

How to write plugins for HAbE v2.pdf

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